Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy

Authors: Stephanie J. Wang, Ran Li, Thomas S. C. Ng, Gaurav Luthria, Madeleine J. Oudin, Mark Prytyskach, Rainer H. Kohler, Ralph Weissleder, Douglas A. Lauffenburger, Miles A. Miller

Published: 2020-05-22

DOI: 10.1126/sciadv.aaz8521

Source: Full article

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Abstract

Combining multicellular signaling profiles with in vivo imaging reveals how nanotherapy can block local resistance pathways.