A distinct class of plant and animal viral proteins that disrupt mitosis by directly interrupting the mitotic entry switch Wee1-Cdc25-Cdk1

Authors: Huaibing Jin, Zhiqiang Du, Yanjing Zhang, Judit Antal, Zongliang Xia, Yan Wang, Yang Gao, Xiaoge Zhao, Xinyun Han, Yanjun Cheng, Qianhua Shen, Kunpu Zhang, Robert E. Elder, Zsigmond Benko, Csaba Fenyvuesvolgyi, Ge Li, Dionne Rebello, Jing Li, Shilai Bao, Richard Y. Zhao, Daowen Wang

Published: 2020-05-13

DOI: 10.1126/sciadv.aba3418

Source: Full article

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Abstract

A distinct class of mitosis regulators, conserved between plant and animal viruses, play active roles in viral pathogenesis.