GDNF rescues the fate of neural progenitor grafts by attenuating Notch signals in the injured spinal cord in rodents

Authors: Mohamad Khazaei, Christopher S. Ahuja, Hiroaki Nakashima, Narihito Nagoshi, Lijun Li, Jian Wang, Jonathon Chio, Anna Badner, David Seligman, Ayaka Ichise, Shinsuke Shibata, Michael G. Fehlings

Published: 2020-01-09

DOI: 10.1126/scitranslmed.aau3538

Source: Full article

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Abstract

Glial-derived neurotrophic factor expression by grafted human neural progenitor cells enhances functional recovery after spinal cord injury.