Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice

Authors: Parag Kundu, Hae Ung Lee, Isabel Garcia-Perez, Emmy Xue Yun Tay, Hyejin Kim, Llanto Elma Faylon, Katherine A. Martin, Rikky Purbojati, Daniela I. Drautz-Moses, Sujoy Ghosh, Jeremy K. Nicholson, Stephan Schuster, Elaine Holmes, Sven Pettersson

Published: 2019-11-14

DOI: 10.1126/scitranslmed.aau4760

Source: Full article

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Abstract

Transplantation of the gut microbiota of old donor mice into young germ-free mice promotes neurogenesis and prolongevity gene expression signatures.