Supercharging adoptive T cell therapy to overcome solid tumor–induced immunosuppression

Authors: Sherly Mardiana, Benjamin J. Solomon, Phillip K. Darcy, Paul A. Beavis

Published: 2019-06-05

DOI: 10.1126/scitranslmed.aaw2293

Source: Full article

---

Abstract

Immune checkpoints can be targeted using exogenous reagents or via genetic modification to enhance the efficacy of adoptive T cell therapy.