Distinct neural mechanisms for the prosocial and rewarding properties of MDMA

Authors: Boris D. Heifets, Juliana S. Salgado, Madison D. Taylor, Paul Hoerbelt, Daniel F. Cardozo Pinto, Elizabeth E. Steinberg, Jessica J. Walsh, Ji Y. Sze, Robert C. Malenka

Published: 2019-12-12

DOI: 10.1126/scitranslmed.aaw6435

Source: Full article

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Abstract

MDMA, which has both therapeutic and abuse potential, engages a brain region–specific serotonergic pathway to produce its prosocial effect.