LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling

Authors: JingHong Wan, Emmanuel Weiss, Sanae Ben Mkaddem, Morgane Mabire, Pierre-Marie Choinier, Olivia Picq, Tristan Thibault-Sogorb, Pushpa Hegde, Dorsa Pishvaie, Marcelle Bens, Linda Broer, Hélène Gilgenkrantz, Richard Moreau, Loredana Saveanu, Patrice Codogno, Renato C. Monteiro, Sophie Lotersztajn

Published: 2020-04-15

DOI: 10.1126/scitranslmed.aaw8523

Source: Full article

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Abstract

LC3-associated phagocytosis is a protective mechanism against inflammation, with antifibrogenic properties in the liver.