Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans

Authors: Liam Chung, David R. Maestas, Andriana Lebid, Ashlie Mageau, Gedge D. Rosson, Xinqun Wu, Matthew T. Wolf, Ada J. Tam, Isabel Vanderzee, Xiaokun Wang, James I. Andorko, Hong Zhang, Radhika Narain, Kaitlyn Sadtler, Hongni Fan, Daniela Čiháková, Claude Jourdan Le Saux, Franck Housseau, Drew M. Pardoll, Jennifer H. Elisseeff

Published: 2020-04-15

DOI: 10.1126/scitranslmed.aax3799

Source: Full article

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Abstract

Interleukin 17 and senescent cells regulate fibrosis in the foreign body response to synthetic material implants.