IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia

Authors: Tian Yi Zhang, Ritika Dutta, Brooks Benard, Feifei Zhao, Raymond Yin, Ravindra Majeti

Published: 2020-04-08

DOI: 10.1126/scitranslmed.aax5104

Source: Full article


Abstract

Acute myeloid leukemia inhibits normal erythroid differentiation through paracrine effects of IL-6.