Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation

Authors: Wing Hing Wong, Sima Bhatt, Kathryn Trinkaus, Iskra Pusic, Kevin Elliott, Nitin Mahajan, Fei Wan, Galen E. Switzer, Dennis L. Confer, John DiPersio, Michael A. Pulsipher, Nirali N. Shah, Jennifer Sees, Amelia Bystry, Jamie R. Blundell, Bronwen E. Shaw, Todd E. Druley

Published: 2020-01-16

DOI: 10.1126/scitranslmed.aax6249

Source: Full article

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Abstract

Donor hematopoietic clones with pathogenic mutations engraft and persist in unrelated hematopoietic stem cell transplant recipients.