A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus

Authors: Jody Hobson-Peters, Jessica J. Harrison, Daniel Watterson, Jessamine E. Hazlewood, Laura J. Vet, Natalee D. Newton, David Warrilow, Agathe M. G. Colmant, Carmel Taylor, Bixing Huang, Thisun B. H. Piyasena, Weng Kong Chow, Yin Xiang Setoh, Bing Tang, Eri Nakayama, Kexin Yan, Alberto A. Amarilla, Sarah Wheatley, Peter R. Moore, Mitchell Finger, Nina Kurucz, Naphak Modhiran, Paul R. Young, Alexander A. Khromykh, Helle Bielefeldt-Ohmann, Andreas Suhrbier, Roy A. Hall

Published: 2019-12-12

DOI: 10.1126/scitranslmed.aax7888

Source: Full article


Abstract

Insect-specific Binjari virus facilitates the production of chimeric virus particles of flavivirus pathogens for diagnostics and vaccines.