Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice

Authors: Kristina G. Maxwell, Punn Augsornworawat, Leonardo Velazco-Cruz, Michelle H. Kim, Rie Asada, Nathaniel J. Hogrebe, Shuntaro Morikawa, Fumihiko Urano, Jeffrey R. Millman

Published: 2020-04-22

DOI: 10.1126/scitranslmed.aax9106

Source: Full article

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Abstract

Patient stem cell–derived β cells corrected for a diabetes-causing variant in