Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model

Authors: Hector R. Wong, J. Timothy Caldwell, Natalie Z. Cvijanovich, Scott L. Weiss, Julie C. Fitzgerald, Michael T. Bigham, Parag N. Jain, Adam Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Christopher J. Lindsell

Published: 2019-11-14

DOI: 10.1126/scitranslmed.aax9000

Source: Full article

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Abstract

Prognostic biomarkers for pediatric septic shock are conserved in a murine model of sepsis and accelerate testing of precision medicine strategies.