Near-infrared nerve-binding fluorophores for buried nerve tissue imaging

Authors: Lei G. Wang, Connor W. Barth, Catherine H. Kitts, Mubark D. Mebrat, Antonio R. MontaƱo, Broderick J. House, Meaghan E. McCoy, Alexander L. Antaris, S. N. Galvis, Ian McDowall, Jonathan M. Sorger, Summer L. Gibbs

Published: 2020-05-06

DOI: 10.1126/scitranslmed.aay0712

Source: Full article


Abstract

Small-molecule near-infrared nerve contrast agents were developed to enable nerve visualization at depth, improving nerve-sparing during surgery.