An open-label phase 1/2a trial of a genetically modified rodent malaria parasite for immunization against

Authors: Isaie J. Reuling, António M. Mendes, Gerdie M. de Jong, Amanda Fabra-García, Helena Nunes-Cabaço, Geert-Jan van Gemert, Wouter Graumans, Luc E. Coffeng, Sake J. de Vlas, Annie S. P. Yang, Cynthia Lee, Yimin Wu, Ashley J. Birkett, Christian F. Ockenhouse, Rob Koelewijn, Jaap J. van Hellemond, Perry J. J. van Genderen, Robert W. Sauerwein, Miguel Prudêncio

Published: 2020-05-20

DOI: 10.1126/scitranslmed.aay2578

Source: Full article


Abstract

Clinical evaluation of genetically modified rodent malaria parasites for whole-sporozoite immunization against