Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite

Authors: Laura-Oana Albulescu, Melissa S. Hale, Stuart Ainsworth, Jaffer Alsolaiss, Edouard Crittenden, Juan J. Calvete, Chloe Evans, Mark C. Wilkinson, Robert A. Harrison, Jeroen Kool, Nicholas R. Casewell

Published: 2020-05-06

DOI: 10.1126/scitranslmed.aay8314

Source: Full article

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Abstract

DMPS, a drug licensed to treat mercury poisoning, is preclinically effective as an oral therapeutic for treating certain hemotoxic snakebites.