Breaking the bond between tetranectin and HMGB1 in sepsis

Authors: Cameron W. Paterson, Mandy L. Ford, Craig M. Coopersmith

Published: 2020-04-15

DOI: 10.1126/scitranslmed.abb2575

Source: Full article


Abstract

The interaction between tetranectin and high-mobility group box-1 may be manipulated via monoclonal antibodies to improve survival in sepsis (Chen