Stress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustained activation of SAPKs by oxidative stress

Authors: Moe Matsushita, Takanori Nakamura, Hisashi Moriizumi, Hiroaki Miki, Mutsuhiro Takekawa

Published: 2020-06-24

DOI: 10.1126/sciadv.aay9778

Source: Full article

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Abstract

A new oxidative-stress sensor, MTK1, regulates the duration and magnitude of SAPK signaling to dictate cell fate decisions.