Annexin A1–dependent tethering promotes extracellular vesicle aggregation revealed with single–extracellular vesicle analysis

Authors: Maximillian A. Rogers, Fabrizio Buffolo, Florian Schlotter, Samantha K. Atkins, Lang H. Lee, Arda Halu, Mark C. Blaser, Elena Tsolaki, Hideyuki Higashi, Kristin Luther, George Daaboul, Carlijn V.C. Bouten, Simon C. Body, Sasha A. Singh, Sergio Bertazzo, Peter Libby, Masanori Aikawa, Elena Aikawa

Published: 2020-09-16

DOI: 10.1126/sciadv.abb1244

Source: Full article

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Abstract

Protein-mediated tethering of vesicles in the extracellular matrix contributes to microcalcification formation.