TRPML2 is an osmo/mechanosensitive cation channel in endolysosomal organelles

Authors: Cheng-Chang Chen, Einar Krogsaeter, Elisabeth S. Butz, Yanfen Li, Rosa Puertollano, Christian Wahl-Schott, Martin Biel, Christian Grimm

Published: 2020-11-12

DOI: 10.1126/sciadv.abb5064

Source: Full article

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Abstract

Protein trafficking is mediated by tubulation/vesiculation of endosomes and is regulated by osmo/mechanosensitive TRPML2.