Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury

Authors: Sandrine Ettou, Youngsook L. Jung, Tomoya Miyoshi, Dhawal Jain, Ken Hiratsuka, Valerie Schumacher, Mary E. Taglienti, Ryuji Morizane, Peter J. Park, Jordan A. Kreidberg

Published: 2020-07-24

DOI: 10.1126/sciadv.abb5460

Source: Full article

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Abstract

The Wilms tumor-1 transcription factor regulates a repair process, providing insights on the pathogenesis of kidney disease.