Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy

Authors: Xuefei Zhou, Yun Liu, Mengying Hu, Menglin Wang, Xiangrui Liu, Leaf Huang

Published: 2021-02-17

DOI: 10.1126/sciadv.abb6596

Source: Full article

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Abstract

Macrophages can be modulated with relaxin gene delivery to promote cancer fibrosis regression and T cell infiltration.