ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule

Authors: Di Liu, Gaofeng Shu, Feiyang Jin, Jing Qi, Xiaoling Xu, Yan Du, Hui Yu, Jun Wang, Mingchen Sun, Yuchan You, Minxia Zhu, Meixuan Chen, Luwen Zhu, Qiying Shen, Xiaoying Ying, Xuefang Lou, Saiping Jiang, Yongzhong Du

Published: 2020-10-09

DOI: 10.1126/sciadv.abb7422

Source: Full article

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Abstract

An SS31 prodrug improved AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule.