cGAS suppresses genomic instability as a decelerator of replication forks

Authors: Hao Chen, Hao Chen, Jiamin Zhang, Yumin Wang, Antoine Simoneau, Hui Yang, Arthur S. Levine, Lee Zou, Zhijian Chen, Li Lan

Published: 2020-10-14

DOI: 10.1126/sciadv.abb8941

Source: Full article

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Abstract

cGAS controls replication dynamics and suppresses replication-associated DNA damage.