Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

Authors: Chatrin Chatrin, Mads Gabrielsen, Lori Buetow, Mark A. Nakasone, Syed F. Ahmed, David Sumpton, Gary J. Sibbet, Brian O. Smith, Danny T. Huang

Published: 2020-09-18

DOI: 10.1126/sciadv.abc0418

Source: Full article

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Abstract

The C-terminal RING and DTC domains of mammalian Deltex proteins catalyze ADP-ribosylation at the C terminus of ubiquitin.