Synthetic lethality across normal tissues is strongly associated with cancer risk, onset, and tumor suppressor specificity

Authors: Kuoyuan Cheng, Nishanth Ulhas Nair, Joo Sang Lee, Eytan Ruppin

Published: 2021-01-01

DOI: 10.1126/sciadv.abc2100

Source: Full article

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Abstract

Expression pattern of synthetic lethality genes is a previously unknown factor associated with cancer risk across human tissues.