Determinants of seeding and spreading of α-synuclein pathology in the brain

Authors: Martin T. Henrich, Fanni F. Geibl, Harini Lakshminarasimhan, Anna Stegmann, Benoit I. Giasson, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Wolfgang H. Oertel, D. James Surmeier

Published: 2020-11-12

DOI: 10.1126/sciadv.abc2487

Source: Full article

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Abstract

The uptake and spread of a-synuclein pathology in the brain are governed by neuronal phenotype and connectomics.