Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization

Authors: Franziska Mueller, Alexandra Friese, Claudio Pathe, Richard Cardoso da Silva, Kenny Bravo Rodriguez, Andrea Musacchio, Tanja Bange

Published: 2021-01-15

DOI: 10.1126/sciadv.abc8590

Source: Full article

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Abstract

N-terminal acetylation by NATA acetyltransferase shields many of its targets from inhibitor of apoptosis ubiquitin ligases.