Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle

Authors: Yool Lee, Shi Yi Fong, Joy Shon, Shirley L. Zhang, Rebekah Brooks, Nicholas F. Lahens, Dechun Chen, Chi Van Dang, Jeffrey M. Field, Amita Sehgal

Published: 2021-02-14

DOI: 10.1126/sciadv.abd2645

Source: Full article

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Abstract

Circadian regulation of tumors provides a basis for chemotherapy at specific times of day.