Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis

Authors: Capucine L. Grandjean, Zacarias Garcia, Fabrice Lemaître, Béatrice Bréart, Philippe Bousso

Published: 2021-02-19

DOI: 10.1126/sciadv.abd6167

Source: Full article

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Abstract

The mechanism and limitations of anti-CD20 therapy, a major treatment for B cell lymphomas, were uncovered using in vivo imaging.