Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver

Authors: Bhoomika Mathur, Asif Shajahan, Waqar Arif, Qiushi Chen, Nicholas J. Hand, Lara K. Abramowitz, Kristina Schoonjans, Daniel J. Rader, Auinash Kalsotra, John A. Hanover, Parastoo Azadi, Sayeepriyadarshini Anakk

Published: 2021-04-22

DOI: 10.1126/sciadv.abf4865

Source: Full article

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Abstract

Loss of two hepatic nuclear receptors muddles the Golgi and the sugarcoat on proteins.