Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response

Authors: Yarden Ariav, James H Ch’ng, Heather R. Christofk, Noga Ron-Harel, Ayelet Erez

Published: 2021-05-19

DOI: 10.1126/sciadv.abg6165

Source: Full article


Abstract

Understanding the dependence of cancers and virus-infected and immune cells on nucleotides can tilt the balance to benefit therapy.