Aptamers against mouse and human tumor-infiltrating myeloid cells as reagents for targeted chemotherapy

Authors: Adriana De La Fuente, Serena Zilio, Jimmy Caroli, Dimitri Van Simaeys, Emilia M. C. Mazza, Tan A. Ince, Vincenzo Bronte, Silvio Bicciato, Donald T. Weed, Paolo Serafini

Published: 2020-06-17

DOI: 10.1126/scitranslmed.aav9760

Source: Full article

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Abstract

Aptamers specific for mouse and human tumor-infiltrating myeloid cells allow anticancer drug delivery to the tumor microenvironment in mouse models.