Necrotizing enterocolitis induces T lymphocyte–mediated injury in the developing mammalian brain

Authors: Qinjie Zhou, Diego F. Niño, Yukihiro Yamaguchi, Sanxia Wang, William B. Fulton, Hongpeng Jia, Peng Lu, Thomas Prindle, David Pamies, Meaghan Morris, Liam L. Chen, Chhinder P. Sodhi, David J. Hackam

Published: 2021-01-06

DOI: 10.1126/scitranslmed.aay6621

Source: Full article

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Abstract

Brain injury in necrotizing enterocolitis requires an influx of gut-derived IFN-γ–releasing T lymphocytes into the developing mouse and human brain.