Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia

Authors: Bernd B. Zeisig, Tsz Kan Fung, Magdalena Zarowiecki, Chiou Tsun Tsai, Huacheng Luo, Boban Stanojevic, Claire Lynn, Anskar Y. H. Leung, Jan Zuna, Marketa Zaliova, Martin Bornhauser, Malte von Bonin, Boris Lenhard, Suming Huang, Ghulam J. Mufti, Chi Wai Eric So

Published: 2021-02-24

DOI: 10.1126/scitranslmed.abc4822

Source: Full article

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Abstract

Chemoresistant human CD34