Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer

Authors: Qian Zhang, Ziting Chen, Fangzhu Wang, Siqi Zhang, Hongyu Chen, Xueying Gu, Fengcai Wen, Jiachuan Jin, Xia Zhang, Xingxu Huang, Bin Shen, Bo Sun

Published: 2021-10-27

DOI: 10.1093/nar/gkab1139

Source: Full article

Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer

Abstract