Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer

Authors: Ana Nikolic, Divya Singhal, Katrina Ellestad, Michael Johnston, Yaoqing Shen, Aaron Gillmor, Sorana Morrissy, J. Gregory Cairncross, Steven Jones, Mathieu Lupien, Jennifer A. Chan, Paola Neri, Nizar Bahlis, Marco Gallo

Published: 2021-10-13

DOI: 10.1126/sciadv.abg6045

Source: Full article

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Abstract

Inferring structural variants in cancer single-cell chromatin accessibility data links genetics to chromatin organization.