The CCL2-CCR2 astrocyte-cancer cell axis in tumor extravasation at the brain

Authors: Cynthia Hajal, Yoojin Shin, Leanne Li, Jean Carlos Serrano, Tyler Jacks, Roger D. Kamm

Published: 2021-06-23

DOI: 10.1126/sciadv.abg8139

Source: Full article

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Abstract

Astrocyte-secreted CCL2 promotes cancer cell extravasation at the brain via chemotaxis and chemokinesis.