Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor

Authors: Marie Saitou, Skyler Resendez, Apoorva J. Pradhan, Fuguo Wu, Natasha C. Lie, Nancy J. Hall, Qihui Zhu, Laura Reinholdt, Yoko Satta, Leo Speidel, Shigeki Nakagome, Neil A. Hanchard, Gary Churchill, Charles Lee, G. Ekin Atilla-Gokcumen, Xiuqian Mu, Omer Gokcumen

Published: 2021-09-24

DOI: 10.1126/sciadv.abi4476

Source: Full article

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Abstract

The evolutionary history of a common genetic variant is linked to its sex-specific effect on response to nutritional stress.