MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade

Authors: Qinbo Cai, Wolong Zhou, Wei Wang, Bingning Dong, Dong Han, Tao Shen, Chad J. Creighton, David D. Moore, Feng Yang

Published: 2021-11-12

DOI: 10.1126/sciadv.abi6439

Source: Full article

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Abstract

MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase inhibitors.