TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity

Authors: Jiacheng Bi, Chen Cheng, Chaoyue Zheng, Chen Huang, Xiaohu Zheng, Xiaochun Wan, Youhai H. Chen, Zhigang Tian, Haoyu Sun

Published: 2021-09-15

DOI: 10.1126/sciadv.abi6515

Source: Full article

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Abstract

TIPE2 suppresses NK cells to reach an optimal functional status and NK cell antitumor immunity.