Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization

Authors: Erica A. Moehle, Ryo Higuchi-Sanabria, C. Kimberly Tsui, Stefan Homentcovschi, Kevin M. Tharp, Hanlin Zhang, Hannah Chi, Larry Joe, Mattias de los Rios Rogers, Arushi Sahay, Naame Kelet, Camila Benitez, Raz Bar-Ziv, Gilberto Garcia, Koning Shen, Phillip A. Frankino, Robert T. Schinzel, Ophir Shalem, Andrew Dillin

Published: 2021-10-29

DOI: 10.1126/sciadv.abj6818

Source: Full article

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Abstract

Cross-species genetic screens for mitochondrial regulators revealed EPS-8 as a link between actin stability and mitochondria.