Calcineurin and huntingtin form a calcium-sensing machinery that directs neurotrophic signals to the nucleus

Authors: Chiara Scaramuzzino, Emeline C. Cuoc, Patrick Pla, Sandrine Humbert, Frédéric Saudou

Published: 2022-01-05

DOI: 10.1126/sciadv.abj8812

Source: Full article

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Abstract

Neurotrophin-bearing endosomes respond to local calcium concentrations to self-direct long-range retrograde transport.