MLL4 mediates differentiation and tumor suppression through ferroptosis

Authors: Shaun Egolf, Jonathan Zou, Amy Anderson, Cory L. Simpson, Yann Aubert, Stephen Prouty, Kai Ge, John T. Seykora, Brian C. Capell

Published: 2021-12-10

DOI: 10.1126/sciadv.abj9141

Source: Full article

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Abstract

This study reveals how epigenetic errors drive skin cancer initiation via altered cell fate and impaired ferroptosis.