Computer-aided design of reversible hybridization chain reaction (CAD-HCR) enables multiplexed single-cell spatial proteomics imaging

Authors: Xiaohao Liu, Dongsheng Mao, Yuchen Song, Liucun Zhu, Albertina N. Isak, Cuicui Lu, Guoli Deng, Feng Chen, Fenyong Sun, Yu Yang, Xiaoli Zhu, Weihong Tan

Published: 2022-01-14

DOI: 10.1126/sciadv.abk0133

Source: Full article

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Abstract

Cyclic imaging of multiple proteins in a single cell is realized through CAD-HCR.