A viral ubiquitination switch attenuates innate immunity and triggers nuclear import of virion DNA and infection

Authors: Michael Bauer, Alfonso Gomez-Gonzalez, Maarit Suomalainen, Nicolas Schilling, Silvio Hemmi, Urs F. Greber

Published: 2021-12-17

DOI: 10.1126/sciadv.abl7150

Source: Full article

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Abstract

The E3 ubiquitin ligase Mib1 and proteasome promote infection by releasing the linchpin protein V from incoming adenovirus.