Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma

Authors: Mario Fidanza, Puja Gupta, Anin Sayana, Varun Shanker, Svenja-Maria Pahlke, Brandon Vu, Fanny Krantz, Aruna Azameera, Nicollette Wong, Navya Anne, Yuanxuan Xia, Jiming Rong, Avani Anne, Stephen Skirboll, Michael Lim, Albert J. Wong

Published: 2021-06-16

DOI: 10.1126/scitranslmed.aax4100

Source: Full article

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Abstract

Increasing proteasomal processing efficiency by targeted modification of a peptide vaccine improves survival in a glioblastoma model.