Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment

Authors: Shuang Wang, Feng Li, Tong Ye, Jianghua Wang, Chengliang Lyu, Shuang Qing, Zhaowen Ding, Xiaoyong Gao, Rongrong Jia, Di Yu, Jun Ren, Wei Wei, Guanghui Ma

Published: 2021-10-13

DOI: 10.1126/scitranslmed.abb6981

Source: Full article

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Abstract

Macrophage-tumor chimeric exosomes inhibit tumor growth in multiple mouse models by stimulating the immune response and tumor microenvironment.