Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro

Authors: Miguel Reyes, Michael R. Filbin, Roby P. Bhattacharyya, Abraham Sonny, Arnav Mehta, Kianna Billman, Kyle R. Kays, Mayra Pinilla-Vera, Maura E. Benson, Lisa A. Cosimi, Deborah T. Hung, Bruce D. Levy, Alexandra-Chloe Villani, Moshe Sade-Feldman, Rebecca M. Baron, Marcia B. Goldberg, Paul C. Blainey, Nir Hacohen

Published: 2021-06-08

DOI: 10.1126/scitranslmed.abe9599

Source: Full article

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Abstract

Cytokines in plasma from sepsis or severe COVID-19 patients induce production of suppressive myeloid cells from hematopoietic progenitors in vitro.