Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity

Authors: Katharina Lambert, Keagan G. Moo, Azlann Arnett, Gautam Goel, Alex Hu, Kaitlin J. Flynn, Cate Speake, Alice E. Wiedeman, Vivian H. Gersuk, Peter S. Linsley, Carla J. Greenbaum, S. Alice Long, Rebecca Partridge, Jane H. Buckner, Bernard Khor

Published: 2022-01-12

DOI: 10.1126/scitranslmed.abi4888

Source: Full article

---

Abstract

Permutational analysis of the immune system reveals advanced immune aging in individuals with Down syndrome and in individuals with type 1 diabetes.